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Invitrogen™ PTPRB Polyclonal Antibody
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Catalog No. PIPA5119373
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200 μL
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PIPA5119373 200 μL
PIPA5121857 20 μL
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Catalog No. PIPA5119373 Supplier Invitrogen™ Supplier No. PA5119373
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Description

Rabbit Polyclonal Antibody

PTPRB Polyclonal Antibody for IHC (P)

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTPRB
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene PTPRB
Gene Accession No. B2RU80
Gene Alias 3230402H02Rik; C130094E24; HPTPB; HPTP-BETA; protein tyrosine phosphatase, receptor type B; protein tyrosine phosphatase, receptor type, B; protein tyrosine phosphatase, receptor type, beta polypeptide; protein-tyrosine phosphatase beta; PTPB; Ptprb; Ptpz; receptor-type tyrosine-protein phosphatase beta; Rptpb; R-PTP-BETA; vascular endothelial protein tyrosine phosphatase; VEPTP; VE-PTP
Gene Symbols PTPRB
Host Species Rabbit
Immunogen Recombinant protein Tyrosine Phosphatase Receptor Type B. The antigen corresponds to amino acid range 1214-1463 of the target protein.
Purification Method Protein A, Antigen affinity chromatography
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19263
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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