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PTPRCAP Polyclonal Antibody, Invitrogen™

Catalog No. PIPA5118224
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100 μL
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PIPA5118224 100 μL
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Catalog No. PIPA5118224 Supplier Thermo Scientific Supplier No. PA5118224
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Description

Rabbit Polyclonal Antibody

MSK-1 is a mitogen and stress activated protein kinase-1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily. MSK-1 can be activated by ERK1/2 and SAPK2 /p38 MAP kinase. It is also known to be required for the phosphorylation of CREB, ATF1 H3 and HMG-14 in response to mitogen and stress. Similar to RSK, MSK-1 contains two kinase domains (N-term and a C-term). Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, MSK-1 autophosphorylate on at least 5 sites. Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C-terminal kinase domain of MSK-1 which is essential for the catalytic activity of the N-terminal kinase domain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTPRCAP
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.03% ProClin 300; pH 7
Gene PTPRCAP
Gene Accession No. Q14761
Gene Alias AI605264; CD45 associated protein; CD-45-AP; CD45-AP; CD45-associated protein; LPAP; LSM-1; Lymphocyte phosphatase-associated phosphoprotein; protein tyrosine phosphatase receptor type C-associated protein; protein tyrosine phosphatase, receptor type C associated protein; protein tyrosine phosphatase, receptor type, C polypeptide-associated protein; protein tyrosine phosphatase, receptor type, C-associated protein; Ptprcap; PTPRC-associated protein
Gene Symbols PTPRCAP
Host Species Rabbit
Immunogen E. coli-derived Human PTPRCAP fragment
Purification Method Antigen affinity chromatography, Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5790
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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