Invitrogen™ PTPRD Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597116

Catalog No. PIPA597116

Description

Immunogen sequence: QITTIGNLVP QKTYSVKVLA FTSIGDGPLS SDIQVITQTG VPGQPLNFKA EPESETSILL SWTPPRSDTI ANYELVYKDG EHGEEQRITI EPGTSYRLQG; Positive Samples: HT-1080, DU145, B cells, Mouse heart; Cellular Location: Membrane, Single-pass type I membrane protein.

PTPRD is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance.

Specifications

• Antigen: PTPRD
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PTPRD
• Gene Alias: 1110002J03Rik; 3000002J10Rik; B230219D21Rik; HPTP; HPTPD; HPTPDELTA; protein tyrosine phosphatase, receptor type D; protein tyrosine phosphatase, receptor type, D; protein tyrosine phosphatase, receptor type, delta polypeptide; Protein-tyrosine phosphatase delta; PTPD; Ptprd; receptor-type tyrosine-protein phosphatase delta; RPTPDELTA; R-PTP-delta
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19266, 5789
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.13 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P23468, Q64487
• Gene Symbols: PTPRD
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 475-574 of human PTPRD (NP_0028301).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG