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Invitrogen™ PTPRE Polyclonal Antibody
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Catalog No. PIPA5121078
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100 μL
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PIPA5121078 100 μL
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Catalog No. PIPA5121078 Supplier Invitrogen™ Supplier No. PA5121078
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Description

Rabbit Polyclonal Antibody

Positive test controls include: HL-60, SW620, Mouse brain, Mouse spleen, Mouse lung, Rat brain, Rat lung. The target is usually found in the following locations: Cell membrane, Cytoplasm, Cytoplasm, Single-pass type I membrane protein. Immunogen sequence: LRGNETTADS NETTTTSGPP DPGASQPLLA WLLLPLLLLL LVLLLAAYFF RFRKQRKAVV STSDKKMPNG ILEEQEQQRV MLLSRSPSGP KKYFPIPVEH LEEEIRIRSA DDCKQFREEF NSLPSGHIQG TFELANKEEN REKNRYPNIL PNDHSRVILS QLDGIPCSDY INASYIDGYK E.

The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTPRE
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.98 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PTPRE
Gene Accession No. B2GV87, P23469, P49446
Gene Alias HPTPE; protein tyrosine phosphatase epsilon; protein tyrosine phosphatase epsilon-like 1; protein tyrosine phosphatase epsilon-like 2; protein tyrosine phosphatase, receptor type E; protein tyrosine phosphatase, receptor type, E; protein tyrosine phosphatase, receptor type, epsilon; protein tyrosine phosphatase, receptor type, epsilon polypeptide; protein-tyrosine phosphatase epsilon; PTP epsilon; PTPE; PTPepsilon; PTPRE; PTPvarepsilon; receptor-type tyrosine-protein phosphatase epsilon; RPTPepsilon; R-PTP-epsilon
Gene Symbols PTPRE
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114767, 19267, 5791
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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