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Invitrogen™ PTPRG Polyclonal Antibody
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Catalog No. PIPA566673
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100 μL
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PIPA566673 100 μL
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Catalog No. PIPA566673 Supplier Invitrogen™ Supplier No. PA566673
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ALHENRHGSAV QIRRRKASGD PYWAYSGAYG PEHWVTSSVS CGGRHQSPID ILDQYARVGE EYQELQLDGF DNESSNKTWM KNTGKTVAIL LKDDYFVS Highest antigen sequence identity to the following orthologs - mouse 90%, rat 70%.

RPTP gamma, also known as Receptor-type tyrosine-protein phosphatase gamma, R-PTP-gamma or PTPRG is a protein tyrosine phosphatase (PTP) is a candidate tumor suppressor gene since it is located on human chromosome 3p14.2-p21, a region frequently deleted in certain types of renal and lung carcinomas. In situ hybridization analysis reveals that RPTP gamma mRNA is expressed in specific regions of the brain and that the localization of RPTP gamma changes during brain development. RPTP gamma is composed of a putative extracellular domain, a single transmembrane domain, and a cytoplasmic portion with two tandem catalytic tyrosine phosphatase domains. The extracellular domain contains a stretch of 266 amino acids with striking homology to the zinc-containing enzyme carbonic anhydrase (CAH), indicating that RPTP gamma and RPTP beta (HPTP zeta) represent a subfamily of receptor tyrosine phosphatases. RPTP gamma may have a function other than catalysis of hydration of metabolic CO2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTPRG
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PTPRG
Gene Accession No. P23470
Gene Alias 5430405N12Rik; AW046354; AW549872; H_RG317H01.1; HPTPG; protein tyrosine phosphatase gamma; protein tyrosine phosphatase, receptor type G; protein tyrosine phosphatase, receptor type, G; protein tyrosine phosphatase, receptor type, gamma polypeptide; protein-tyrosine phosphatase gamma; Protein-tyrosine phosphatase gamma precursor (R-PTP-gamma); Ptpg; Ptprg; receptor type protein tyrosine phosphatase gamma; receptor tyrosine phosphatase gamma; receptor-like protein tyrosine phosphatase gamma; receptor-type protein phosphatase gamma; receptor-type tyrosine-protein phosphatase gamma; RPTP gamma A; RPTP gamma B; RPTP gamma C; RPTP gamma S; RPTPG; RPTPgamma; R-PTP-GAMMA
Gene Symbols PTPRG
Host Species Rabbit
Immunogen Recombinant Human RPTP gamma. Recombinant protein control fragment (Product #RP-107321).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5793
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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