Invitrogen™ PTPRM Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA534142

Catalog No. PIPA534142

Description

Percent identity with other species by BLAST analysis: Human, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Bovine, Bat, Horse, Rabbit (100%) Opossum, Chicken (94%).

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.

Specifications

• Antigen: PTPRM
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PTPRM
• Gene Alias: hR-PTPu; Kiaa4044; MGC166994; mKIAA4044; protein tyrosine phosphatase mu; protein tyrosine phosphatase receptor type M; protein tyrosine phosphatase receptor-type M; protein tyrosine phosphatase, receptor type M; protein tyrosine phosphatase, receptor type, M; protein tyrosine phosphatase, receptor type, mu polypeptide; protein tyrosine phosphatase, receptor-type, M; protein-tyrosine phosphatase mu; PTP mu; Ptpmu; PTPRL1; PTPRM; receptor-type tyrosine-protein phosphatase mu; RPTPM; RPTPmu; R-PTP-MU; RPTPU
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100059664, 100356969, 100761852, 19274, 29616, 536092, 5797
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: P28827, P28828
• Gene Symbols: PTPRM
• Immunogen: Synthetic 16 amino acid peptide from internal region of human PTPRM.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Rabbit, Monkey, Bovine, Hamster, Horse, Bat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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