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Invitrogen™ PTPRN2 Polyclonal Antibody
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Catalog No. PIPA555367
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100 μL
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PIPA555367 100 μL
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Catalog No. PIPA555367 Supplier Invitrogen™ Supplier No. PA555367
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RFSESILTYV AHTSALTYPP GSRTQLREDL LPRTLGQLQP DELSPKVDSG VDRHHLMAAL SAYAAQRPPA PPGEGSLEPQ YLLRAPSRMP RPLLAPAAPQ KWPSPLGDSE DPSST Highest antigen sequence identity to the following orthologs: Mouse - 54%, Rat - 59%.

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTPRN2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PTPRN2
Gene Accession No. Q92932
Gene Alias 4930425H11Rik; EC 3.1.3.48; IA-2 beta; IA2beta; IA-2beta; IA-2beta60; IA-2beta64; IA-2beta71; IAR; IAR/receptor-like protein-tyrosine phosphatase; ICAAR; Islet cell autoantigen-related protein; KIAA0387; mKIAA0387; phogrin; Phol; protein tyrosine phosphatase receptor pi; protein tyrosine phosphatase receptor-type N polypeptide 2; protein tyrosine phosphatase, receptor type N2; protein tyrosine phosphatase, receptor type, N polypeptide 2; protein tyrosine phosphatase, receptor-type, N polypeptide 2; protein tyrosine phosphatase-NP; PTP IA-2beta; PTP NE-6; PTPNE6; PTP-NP; PTPRN2; PTPRP; Receptor-type tyrosine-protein phosphatase N2; R-PTP-N2; tyrosine phosphatase IA-2 beta
Gene Symbols PTPRN2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PTPRN2. Recombinant protein control fragment (Product #RP-88693).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5799
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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