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Invitrogen™ PTPRU Polyclonal Antibody
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Catalog No. PIPA5121203
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100 μL
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PIPA5121203 100 μL
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Catalog No. PIPA5121203 Supplier Invitrogen™ Supplier No. PA5121203
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Description

Rabbit Polyclonal Antibody

Positive test controls include: Mouse brain. The target is usually found in the following locations: Cell junction, Cell membrane, Single-pass type I membrane protein. Immunogen sequence: MARAQALVLA LTFQLCAPET ETPAAGCTFE EASDPAVPCE YSQAQYDDFQ WEQVRIHPGT RAPADLPHGS YLMVNTSQHA PGQRAHVIFQ SLSENDTHCV.

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTPRU
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.37 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene PTPRU
Gene Accession No. B1AUH1
Gene Alias FMI; Ftp-1; GLEPP1; hPTP-J; Pancreatic carcinoma phosphatase 2; Pcp2; PCP-2; pi R-PTP-Psi; protein tyrosine phosphatase, receptor type U; protein tyrosine phosphatase, receptor type, L; protein tyrosine phosphatase, receptor type, U; protein-tyrosine phosphatase J; Protein-tyrosine phosphatase pi; protein-tyrosine phosphatase receptor omicron; Protein-tyrosine phosphatase-lamda; PTP; PTP pi; Ptpf; PTP-J; PTPlambda; PTP-lambda; PTP-PI; PTPPSI; Ptprl; PTPRO; PTP-RO; PTPRU; PTPU2; Receptor protein tyrosine phosphatase hPTP-J; receptor-type protein-tyrosine phosphatase psi; Receptor-type tyrosine-protein phosphatase U; RPTPlambda; R-PTP-psi; R-PTP-U
Gene Symbols PTPRU
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTPRU (NP_005695.3).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116680, 19273
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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