Invitrogen™ PTPRU Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121203

Catalog No. PIPA5121203

Description

Positive test controls include: Mouse brain. The target is usually found in the following locations: Cell junction, Cell membrane, Single-pass type I membrane protein. Immunogen sequence: MARAQALVLA LTFQLCAPET ETPAAGCTFE EASDPAVPCE YSQAQYDDFQ WEQVRIHPGT RAPADLPHGS YLMVNTSQHA PGQRAHVIFQ SLSENDTHCV.

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported.

Specifications

• Antigen: PTPRU
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PTPRU
• Gene Alias: FMI; Ftp-1; GLEPP1; hPTP-J; Pancreatic carcinoma phosphatase 2; Pcp2; PCP-2; pi R-PTP-Psi; protein tyrosine phosphatase, receptor type U; protein tyrosine phosphatase, receptor type, L; protein tyrosine phosphatase, receptor type, U; protein-tyrosine phosphatase J; Protein-tyrosine phosphatase pi; protein-tyrosine phosphatase receptor omicron; Protein-tyrosine phosphatase-lamda; PTP; PTP pi; Ptpf; PTP-J; PTPlambda; PTP-lambda; PTP-PI; PTPPSI; Ptprl; PTPRO; PTP-RO; PTPRU; PTPU2; Receptor protein tyrosine phosphatase hPTP-J; receptor-type protein-tyrosine phosphatase psi; Receptor-type tyrosine-protein phosphatase U; RPTPlambda; R-PTP-psi; R-PTP-U
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116680, 19273
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.37 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: B1AUH1
• Gene Symbols: PTPRU
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTPRU (NP_005695.3).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG