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Invitrogen™ PTX3 Monoclonal Antibody (MNB1)
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Catalog No. FERMA549096
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100 μg
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Catalog No. Quantity
FERMA549096 100 μg
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Catalog No. FERMA549096 Supplier Invitrogen™ Supplier No. MA549096
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Description

Rat Monoclonal Antibody

PTX3 Monoclonal Antibody for Flow, Functional Assay, Inhibition, Western Blot

Pentraxins are a protein superfamily that is characterized by a cyclic multimeric structure. Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents. Ptx3 belongs to the family of 'long pentraxins', which have C-terminal pentraxin domains and novel amino-terminal domains. Ptx3 binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa and Salmonella typhimurium. It is synthesized in IgA glomerulonephritis and activates mesangial cells. Secretion of Ptx3 in adipose cells can be induced by TNF. Ptx3 is also involved in amplification of inflammatory reactions and regulation of innate immunity. The human PTX3 gene maps to chromosome 3q25.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTX3
Applications Flow Cytometry, Functional Assay, Inhibition Assays, Western Blot
Classification Monoclonal
Clone MNB1
Concentration 100 μg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA and no preservative
Gene PTX3
Gene Accession No. P26022
Gene Alias AI607804; long pentraxin 3; pentaxin related; pentaxin-related protein PTX3; pentraxin 3; pentraxin 3, long; pentraxin related; pentraxin related gene; pentraxin-related protein PTX3; Ptx3; TNF alpha-induced protein 5; TNFAIP5; Tsg14; TSG-14; Tumor necrosis factor alpha-induced protein 5; tumor necrosis factor-inducible gene 14 protein; tumor necrosis factor-inducible protein TSG-14
Gene Symbols PTX3
Host Species Rat
Immunogen Human recombinant PTX3.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5806
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2b
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