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Invitrogen™ PTX3 Polyclonal Antibody
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Catalog No. PIPA564410
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100 μL
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PIPA564410 100 μL
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Catalog No. PIPA564410 Supplier Invitrogen™ Supplier No. PA564410
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GFDETLAFSG RLTGFNIWDS VLSNEEIRET GGAESCHIRG NIVGWGVTEI QPHGGAQYVS Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 90%.

Pentraxins are a protein superfamily that is characterized by a cyclic multimeric structure. Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents. Ptx3 belongs to the family of long pentraxins, which have C-terminal pentraxin domains and novel amino-terminal domains. Ptx3 binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa and Salmonella typhimurium. It is synthesized in IgA glomerulonephritis and activates mesangial cells. Secretion of Ptx3 in adipose cells can be induced by TNF. Ptx3 is also involved in amplification of inflammatory reactions and regulation of innate immunity. The human PTX3 gene maps to chromosome 3q25.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTX3
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PTX3
Gene Accession No. P26022
Gene Alias AI607804; long pentraxin 3; pentaxin related; pentaxin-related protein PTX3; pentraxin 3; pentraxin 3, long; pentraxin related; pentraxin related gene; pentraxin-related protein PTX3; Ptx3; TNF alpha-induced protein 5; TNFAIP5; Tsg14; TSG-14; Tumor necrosis factor alpha-induced protein 5; tumor necrosis factor-inducible gene 14 protein; tumor necrosis factor-inducible protein TSG-14
Gene Symbols PTX3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PTX3. Recombinant protein control fragment (Product #RP-104184).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5806
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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