Invitrogen™ PU.1 Monoclonal Antibody (5C7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA517178

Catalog No. PIMA517178

Description

MA5-17178 targets SPI1 in FACS, indirect ELISA, and WB applications and shows reactivity with Human samples. The MA5-17178 immunogen is purified recombinant fragment of human SPI1 (amino acids: 124-271) expressed in E. Coli. MA5-17178 detects SPI1 which has a predicted molecular weight of approximately 42kDa.

This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: PU.1
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.03% sodium azide
• Gene Accession No.: P17947
• Gene Symbols: SPI1
• Immunogen: Purified recombinant fragment of human SPI1 (amino acids: 124-271) expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 6688
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Western Blot
• Clone: 5C7
• Conjugate: Unconjugated
• Gene: SPI1
• Gene Alias: 31 kDa transforming protein; 31 kDa-transforming protein; 31kDa Transforming Protein; Dis1; Dis-1; hCG_25181; hematopoietic transcription factor PU.1; OF; Pu.1; SFFV proviral integration 1; SFFV proviral integration 1 protein; Sfpi1; Sfpi-1; Spi1; SPI-1; Spi-1 proto-oncogene; SPIA; SPI-A; spleen focus forming virus (SFFV) proviral integration oncogene; spleen focus forming virus (SFFV) proviral integration oncogene spi1; spleen focus forming virus proviral integration oncogene spi1; Tcfpu1; Tfpu.1; Transcription factor PU.1; Transcription Factor spi1
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1