Invitrogen™ PU.1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5115807

Catalog No. PIPA5115807

Description

Antibody detects endogenous levels of total PU.1/Spi1.

This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: PU.1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SPI1
• Gene Alias: 31 kDa transforming protein; 31 kDa-transforming protein; 31kDa Transforming Protein; Dis1; Dis-1; hCG_25181; hematopoietic transcription factor PU.1; OF; Pu.1; SFFV proviral integration 1; SFFV proviral integration 1 protein; Sfpi1; Sfpi-1; Spi1; SPI-1; Spi-1 proto-oncogene; SPIA; SPI-A; spleen focus forming virus (SFFV) proviral integration oncogene; spleen focus forming virus (SFFV) proviral integration oncogene spi1; spleen focus forming virus proviral integration oncogene spi1; Tcfpu1; Tfpu.1; Transcription factor PU.1; Transcription Factor spi1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20375, 366126, 6688
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P17433, P17947, Q6BDS1
• Gene Symbols: SPI1
• Immunogen: A synthesized peptide derived from human SPI1(Accession P17947), corresponding to amino acid residues L124-Q174.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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