PUF60 Mouse anti-Human, Mouse, Rat, Clone: GT677, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527822
Positive Control: mouse brain, rat brain, 293T, A431, HeLa, HepG2 Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.PUF60 encodes a protein that is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.
|PBS with no preservative|
|Q3UEB3, Q9UHX1, Q9WV25|
|SIAHBP1, FIR, poly-U binding splicing factor 60KDa, RoBPI|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|22827, 67959, 84401|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Human, Mouse, Rat|
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