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PUF60 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501989877
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50-198-9877 100 μL
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Catalog No. 50-198-9877 Supplier Bioss Supplier No. BS19595R
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Rabbit Polyclonal Antibody

PUF60 encodes a protein that is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.

Specifications

Antigen PUF60
Applications Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation TBS with 1% BSA, 50% glycerol and 0.03% Proclin 300; pH
Gene Puf60
Gene Accession No. Q9UHX1
Gene Alias 2410104I19Rik; 2810454F19Rik; 60 kDa poly(U)-binding-splicing factor; BOS_13660; FBP interacting repressor; FBP-interacting repressor; FIR; FLJ31379; FUSE-binding protein-interacting repressor; LOW QUALITY PROTEIN: poly(U)-binding-splicing factor PUF60; poly(U) binding splicing factor 60; poly(U) binding splicing factor 60KDa; Poly(U)-binding-splicing factor PUF60; poly-U binding splicing factor 60; poly-U binding splicing factor 60K; poly-U binding splicing factor 60KDa; Puf60; pyrimidine tract binding splicing factor; RNA-binding protein Siah-BP; Ro ribonucleoprotein-binding protein 1; Ro-binding protein 1; RoBP1; ROBPI; Siah binding protein 1; siah binding protein 1; FBP interacting repressor; pyrimidine tract binding splicing factor; Ro ribonucleoprotein-binding protein 1; Siah-binding protein 1; Siahbp1; Siah-BP1; VRJS
Gene Symbols Puf60
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human PUF60.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22827
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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