Invitrogen™ PURA Monoclonal Antibody (1D6)

Catalog No.	Quantity
PIMA519766	100 μg

Catalog No. PIMA519766 Supplier Invitrogen™ Supplier No. MA519766

Description

Mouse Monoclonal Antibody

Peptide Sequence: TQGQTIALPA QGLIEFRDAL AKLIDDYGVE EEPAELPEGT SLTVDNKRFF FDVGSNKYGV FMRVSEVKPT YRNSITVPYK VWAKFGHTFC KYSEETKKIQ EKQREKRAAC.

This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.

Specifications

• Antigen: PURA
• Applications: ELISA, Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: 1D6
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative; pH 7.4
• Gene: PURA
• Gene Accession No.: Q00577
• Gene Alias: CAGER-1; MRD31; Pur alpha; PUR1; Pura; pura {ECO:0000250; PURALPHA; Pur-alpha; purine rich element binding protein A; purine-rich element binding protein A; purine-rich single-stranded DNA-binding protein alpha; purine-rich single-stranded DNA-binding protein alpha {ECO:0000250; ssCRE-BP; transcriptional activator protein Pur-alpha; transcriptional activator protein Pur-alpha {ECO:0000250; UniProtKB:P42669}
• Gene Symbols: PURA
• Host Species: Mouse
• Immunogen: PURA (NP_005850, 183 a.a. ~ 292 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Protein A
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5813
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b κ