Invitrogen™ PURA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5113567

Catalog No. PIPA5113567

Description

Immunogen sequence: VEFRDYLGDF IEHYAQLGPS QPPDLAQAQD EPRRALKSEF LVRENRKYYM For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%.

This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.

Specifications

• Antigen: PURA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PURA
• Gene Alias: CAGER-1; MRD31; Pur alpha; PUR1; Pura; pura {ECO:0000250; PURALPHA; Pur-alpha; purine rich element binding protein A; purine-rich element binding protein A; purine-rich single-stranded DNA-binding protein alpha; purine-rich single-stranded DNA-binding protein alpha {ECO:0000250; ssCRE-BP; transcriptional activator protein Pur-alpha; transcriptional activator protein Pur-alpha {ECO:0000250; UniProtKB:P42669}
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5813
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q00577
• Gene Symbols: PURA
• Immunogen: Synthetic peptide directed towards the middle region of human PURA.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov