Puromycin Dihydrochloride, 10 mg/mL in Distilled Water, Sterile-filtered, Thermo Scientific Chemicals PROMO

Description

Puromycin (CAS # 58-58-2) is a bacteriostatic antibiotic that acts as an aminoacyl-tRNA analog and disrupts protein synthesis.

General Description

• Puromycin (puromycine) is an aminoglycoside antibiotic originating from Streptomyces alboniger
• It acts as an aminoacyl tRNA analog and prematurely terminates peptide elongation
• Puromycin has effects on both prokaryotes and eukaryotes
• Puromycin may also have neoplastic activity

Application

• Puromycin can be used for research use as an immunofluorescent target, in antibiotic resistance testing, or for studies on drug mechanisms

Specifications

Chemical Identifiers

• CAS: 58-58-2
• Molecular Formula: C22H31Cl2N7O5
• Molecular Weight (g/mol): 544.43 g/mol
• MDL Number: MFCD00150080
• InChI Key: MKSVFGKWZLUTTO-MLYJQVMKNA-N
• PubChem CID: 439530
• ChEBI: CHEBI:17939
• IUPAC Name: (2S)-2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)-9H-purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide dihydrochloride
• SMILES: Cl.Cl.COC1=CC=C(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)N2C=NC3=C(N=CN=C23)N(C)C)C=C1

• Type: Puromycin Dihydrochloride
• Physical Form: Liquid
• Packaging: Plastic Bottle
• Quantity: 1 mL
• Solubility Information: Soluble in Water (50 mg/mL at 20°C).
• Chemical Name or Material: Puromycin Dihydrochloride

Safety and Handling

Hazard Category	H302
Precautionary Statement	P264b-P270-P301+P312-P330-P501c
RTECSNumber	AU7350000
TSCA	No
Recommended Storage	Store at -20°C

RUO – Research Use Only