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Alfa Aesar™ Puromycin dihydrochloride, 99%

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Quantity:
25mg
100mg
500mg
58-58-2
C22H31Cl2N7O5
544.434
MFCD00012691
MKSVFGKWZLUTTO-ZKWLAQDLSA-N
131632508
(2S)-2-amino-N-[(2S,3S,4S,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide;dihydrochloride
CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O.Cl.Cl
58-58-2
C22H31Cl2N7O5
544.434
MFCD00012691
MKSVFGKWZLUTTO-ZKWLAQDLSA-N
131632508
(2S)-2-amino-N-[(2S,3S,4S,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide;dihydrochloride
CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O.Cl.Cl

Causes premature chain termination in protein synthesis

Applications
It also exhibits antitumor activity in studies on brain tumor cells. Puromycin is a protein synthesis inhibitor that causes premature chain termination by acting as an analog of the 3¢-terminal end of aminoacyl-tRNA. It has been used to study transcriptional regulatory mechanisms that control the sequential and coordinate expression of genes during cell differentiation.

Solubility
Soluble in water

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Beilstein 3853613
Merck Index 14,7943
Solubility Information Soluble in water
Formula Weight 544.44
Physical Form Powder
Percent Purity 99%
Color White
Melting Point 168°C to 170°C
Quantity 25mg
Chemical Name or Material Puromycin dihydrochloride

GHS H Statement
H302
Harmful if swallowed.

P264b-P270-P301+P312-P330-P501c

H302

EINECSNumber : 200-387-8

RTECSNumber : AU355000

TSCA : No

Recommended Storage : Store at -20°C