Invitrogen™ PUS1 Monoclonal Antibody (3A3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524492

Catalog No. PIMA524492

Description

Peptide Sequence: MAGNAEPPPA GAACPQDRRS CSGRAGGDRV WEDGEHPAKK LKSGGDEERR EKPPKRKIVL LMAYSGKGYH GMQRNVGSSQ FKTIEDDLVS ALVRSGCIPE NHGEDMRKMS FQRCARTDKG VSAAGQVVSL KVWLIDDILE KINSHLPSHI RILGLKRVTG GFNSKNRCDA RTYCYLLPTF AFAHKDRDVQ DETYRLSAET LQQVNRLLAC YKGTHNFHNF TSQKGPQDPS ACRYILEMYC EEPFVREGLE FAVIRVKGQS FMMHQIRKMV GLVVAIVKGY APESVLERSW GTEKVDVPKA PGLGLVLERV HFEKYNQRFG NDGLHEPLDW AQEEGKVAAF KEEHIYPTII GTERDERSMA QWLSTLPIHN FSATALTAGG TGAKVPSPLE GSEGDGDTD.

The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku, which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.

Specifications

• Antigen: PUS1
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q9Y606
• Gene Symbols: PUS1
• Immunogen: PUS1 (AAH02901, 1 a.a. ~ 399 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 3A3
• Conjugate: Unconjugated
• Gene: PUS1
• Gene Alias: A730013B20Rik; mitochondrial tRNA pseudouridine synthase A; MLASA1; MNCb-0873; MPUS1; mPus1p; PP8985; pseudouridine synthase 1; pseudouridylate synthase 1; Pus1; pus1 {ECO:0000312; RGD:1311871}; tRNA pseudouridine synthase A; tRNA pseudouridine synthase A, mitochondrial; tRNA pseudouridine(38-40) synthase; tRNA pseudouridylate synthase I; tRNA uridine isomerase I; tRNA-uridine isomerase I
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 80324
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid