Invitrogen™ PUS1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA585285

Catalog No. PIPA585285

Description

Keep as concentrated solution. Predicted reactivity: Mouse (93%), Rat (93%), Sheep (87%). Positive Control: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse brain. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku, which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.

Specifications

• Antigen: PUS1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PUS1
• Gene Alias: A730013B20Rik; mitochondrial tRNA pseudouridine synthase A; MLASA1; MNCb-0873; MPUS1; mPus1p; PP8985; pseudouridine synthase 1; pseudouridylate synthase 1; Pus1; pus1 {ECO:0000312; RGD:1311871}; tRNA pseudouridine synthase A; tRNA pseudouridine synthase A, mitochondrial; tRNA pseudouridine(38-40) synthase; tRNA pseudouridylate synthase I; tRNA uridine isomerase I; tRNA-uridine isomerase I
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56361, 80324
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9WU56, Q9Y606
• Gene Symbols: PUS1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PUS1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov