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Invitrogen™ PUS1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA597148
Description
Immunogen sequence: YAPESVLERS WGTEKVDVPK APGLGLVLER VHFEKYNQRF GNDGLHEPLD WAQEEGKVAA FKEEHIYPTI IGTERDERSM AQWLSTLPIH NFSATALTAG GTGAKVPSPL EGSEGDGDTD; Positive Samples: U-87MG; Cellular Location: Mitochondrion, Nucleus.
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku, which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.
Specifications
PUS1 | |
Polyclonal | |
Unconjugated | |
PUS1 | |
A730013B20Rik; mitochondrial tRNA pseudouridine synthase A; MLASA1; MNCb-0873; MPUS1; mPus1p; PP8985; pseudouridine synthase 1; pseudouridylate synthase 1; Pus1; pus1 {ECO:0000312; RGD:1311871}; tRNA pseudouridine synthase A; tRNA pseudouridine synthase A, mitochondrial; tRNA pseudouridine(38-40) synthase; tRNA pseudouridylate synthase I; tRNA uridine isomerase I; tRNA-uridine isomerase I | |
Rabbit | |
Affinity chromatography | |
RUO | |
80324 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Western Blot | |
0.54 mg/mL | |
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
Q9Y606 | |
PUS1 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 308-427 of human PUS1 (NP_0794912). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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