Invitrogen™ PUS1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597148

Catalog No. PIPA597148

Description

Immunogen sequence: YAPESVLERS WGTEKVDVPK APGLGLVLER VHFEKYNQRF GNDGLHEPLD WAQEEGKVAA FKEEHIYPTI IGTERDERSM AQWLSTLPIH NFSATALTAG GTGAKVPSPL EGSEGDGDTD; Positive Samples: U-87MG; Cellular Location: Mitochondrion, Nucleus.

The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku, which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.

Specifications

• Antigen: PUS1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PUS1
• Gene Alias: A730013B20Rik; mitochondrial tRNA pseudouridine synthase A; MLASA1; MNCb-0873; MPUS1; mPus1p; PP8985; pseudouridine synthase 1; pseudouridylate synthase 1; Pus1; pus1 {ECO:0000312; RGD:1311871}; tRNA pseudouridine synthase A; tRNA pseudouridine synthase A, mitochondrial; tRNA pseudouridine(38-40) synthase; tRNA pseudouridylate synthase I; tRNA uridine isomerase I; tRNA-uridine isomerase I
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 80324
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.54 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q9Y606
• Gene Symbols: PUS1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 308-427 of human PUS1 (NP_0794912).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov