Invitrogen™ PUS10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA560808

Catalog No. PIPA560808

Description

Immunogen sequence: LVKQEMGKQS LSLGRDDIVQ LKEAYKWITH PLFSEELGVP IDGKSLFEVS VVFAHPETVE DCHFLAAICP DCFKPAKNKQ SVFTRMAVMK A Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 90%.

Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable). Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death.

Specifications

• Antigen: PUS10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Pus10
• Gene Alias: 2810013G11Rik; 4933435A13Rik; AU014648; C77560; CCDC139; coiled-coil domain containing 139; coiled-coil domain-containing protein 139; DOBI; pseudouridine synthase 10; pseudouridylate synthase 10; psi55 synthase; Pus10; Putative tRNA pseudouridine synthase Pus10; RGD1306402; tRNA pseudouridine 55 synthase; tRNA pseudouridylate synthase; tRNA-uridine isomerase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 150962
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q3MIT2
• Gene Symbols: Pus10
• Immunogen: Recombinant protein corresponding to Human PUS10. Recombinant protein control fragment (Product #RP-99687).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG