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Invitrogen™ PUS10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA560808

Catalog No. PIPA560808


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Description

Description

Immunogen sequence: LVKQEMGKQS LSLGRDDIVQ LKEAYKWITH PLFSEELGVP IDGKSLFEVS VVFAHPETVE DCHFLAAICP DCFKPAKNKQ SVFTRMAVMK A Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 90%.

Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable). Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PUS10
Polyclonal
Unconjugated
Pus10
2810013G11Rik; 4933435A13Rik; AU014648; C77560; CCDC139; coiled-coil domain containing 139; coiled-coil domain-containing protein 139; DOBI; pseudouridine synthase 10; pseudouridylate synthase 10; psi55 synthase; Pus10; Putative tRNA pseudouridine synthase Pus10; RGD1306402; tRNA pseudouridine 55 synthase; tRNA pseudouridylate synthase; tRNA-uridine isomerase
Rabbit
Antigen affinity chromatography
RUO
150962
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.3 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q3MIT2
Pus10
Recombinant protein corresponding to Human PUS10. Recombinant protein control fragment (Product #RP-99687).
100 μL
Primary
Human
Antibody
IgG
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