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Invitrogen™ PUS10 Polyclonal Antibody
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Catalog No. PIPA562015
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100 μL
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PIPA562015 100 μL
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Catalog No. PIPA562015 Supplier Invitrogen™ Supplier No. PA562015
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: NSPKAVCAVL EIECAHGAVF VAGRYNKYSR NLPQTPWIID GERKLESSVE ELISDHLLAV FKAESFNFSS SGREDVDVRT LGNGRPFAIE LVNPHRVHFT SQEIKE Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.

Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable). Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PUS10
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Pus10
Gene Accession No. Q3MIT2
Gene Alias 2810013G11Rik; 4933435A13Rik; AU014648; C77560; CCDC139; coiled-coil domain containing 139; coiled-coil domain-containing protein 139; DOBI; pseudouridine synthase 10; pseudouridylate synthase 10; psi55 synthase; Pus10; Putative tRNA pseudouridine synthase Pus10; RGD1306402; tRNA pseudouridine 55 synthase; tRNA pseudouridylate synthase; tRNA-uridine isomerase
Gene Symbols Pus10
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PUS10. Recombinant protein control fragment (Product #RP-99688).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 150962
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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