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Invitrogen™ PUS7 Polyclonal Antibody
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Catalog No. PIPA554983
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100 μL
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PIPA554983 100 μL
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Catalog No. PIPA554983 Supplier Invitrogen™ Supplier No. PA554983
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Rabbit Polyclonal Antibody

Immunogen sequence: PGFDVIYPKH KIQEAYREML TADNLDIDNM RHKIRDYSLS GAYRKIIIRP QNVSWEVVAY DDPKIPLFNT DVDNLEGKTP PVFASEGKYR ALKMDFSLPP STYATMAIRE VLKMDTSIKN QTQ Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.

Pseudouridylate synthase that catalyzes pseudouridylation of RNAs (PubMed:28073919, PubMed:29628141, PubMed:30778726). Acts as a regulator of protein synthesis in embryonic stem cells by mediating pseudouridylation of RNA fragments derived from tRNAs (tRFs): pseudouridylated tRFs inhibit translation by targeting the translation initiation complex (PubMed:29628141). Also catalyzes pseudouridylation of mRNAs: mediates pseudouridylation of mRNAs with the consensus sequence 5'-UGUAG-3' (PubMed:28073919). In addition to mRNAs and tRNAs, binds other types of RNAs, such as snRNAs, Y RNAs and vault RNAs, suggesting that it can catalyze pseudouridylation of many RNA types (PubMed:29628141). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen PUS7
Applications Western Blot, Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PUS7
Gene Accession No. Q96PZ0
Gene Alias C330017I15Rik; FLJ20485; Kiaa1897; pseudouridine synthase 7; pseudouridylate synthase 7; pseudouridylate synthase 7 (putative); pseudouridylate synthase 7 homolog; pseudouridylate synthase 7 homolog (S. cerevisiae); PUS7; RGD1307054
Gene Symbols PUS7
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PUS7. Recombinant protein control fragment (Product #RP-92628).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 296751, 54517, 78697
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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