Invitrogen™ PUS7 Monoclonal Antibody (OTI4H5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA525267

Catalog No. PIMA525267

Description

PUS7 Monoclonal Antibody for Western Blot, Flow

Pseudouridylate synthase that catalyzes pseudouridylation of RNAs (PubMed:28073919, PubMed:29628141, PubMed:30778726). Acts as a regulator of protein synthesis in embryonic stem cells by mediating pseudouridylation of RNA fragments derived from tRNAs (tRFs): pseudouridylated tRFs inhibit translation by targeting the translation initiation complex (PubMed:29628141). Also catalyzes pseudouridylation of mRNAs: mediates pseudouridylation of mRNAs with the consensus sequence 5'-UGUAG-3' (PubMed:28073919). In addition to mRNAs and tRNAs, binds other types of RNAs, such as snRNAs, Y RNAs and vault RNAs, suggesting that it can catalyze pseudouridylation of many RNA types (PubMed:29628141). [UniProt].

Specifications

• Antigen: PUS7
• Classification: Monoclonal
• Concentration: 0.54 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q96PZ0
• Gene Symbols: PUS7
• Immunogen: Full length human recombinant protein of PUS7 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Canine, Monkey
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Western Blot
• Clone: OTI4H5
• Conjugate: Unconjugated
• Gene: PUS7
• Gene Alias: C330017I15Rik; FLJ20485; Kiaa1897; pseudouridine synthase 7; pseudouridylate synthase 7; pseudouridylate synthase 7 (putative); pseudouridylate synthase 7 homolog; pseudouridylate synthase 7 homolog (S. cerevisiae); PUS7; RGD1307054
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100856353, 54517
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid