PXN Mouse anti-Human, Clone: OTI2B8, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF811258

Catalog No. 50-167-0554

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.

Specifications

• Antigen: PXN
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: PXN
• Gene Alias: paxillin
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5829
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI2B8
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P49023
• Gene Symbols: PXN
• Immunogen: Full length human recombit protein of human PXN produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1