PXN Mouse anti-Human, Clone: OTI6G9, lyophilized, TrueMAB™

Catalog No.	Quantity
50-167-0561	100 μg

Catalog No. 50-167-0561 Supplier OriGene Supplier No. CF811265

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.

Specifications

• Antigen: PXN
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI6G9
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: PXN
• Gene Accession No.: P49023
• Gene Alias: paxillin
• Gene Symbols: PXN
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human PXN produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5829
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2a