PYCARD Mouse anti-Human, Clone:1C3D7, Abnova™

Catalog No.	Quantity
89-333-640	100 μg

Catalog No. 89-333-640 Supplier Abnova Corporation Supplier No. MAB17217

Description

Mouse monoclonal antibody raised against recombinant human PYCARD.

This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

• Antigen: PYCARD
• Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 1C3D7
• Conjugate: Unconjugated
• Description: PYD and CARD domain containing
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Immunohistochemistry (1:200-1:1000)
  Immunocytochemistry (1:200-1:1000)
  Flow Cytometry (1:200-1:400)
  The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% sodium azide)
• Gene: PYCARD
• Gene Alias: ASC, CARD5, MGC10332, TMS, TMS-1, TMS1
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acid 1-120 of human PYCARD from E. coli.
• Quantity: 100 μg
• Gene ID (Entrez): 29108
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1