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Invitrogen™ PYDC1 Polyclonal Antibody
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Catalog No. PIPA5102846
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100 μL
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PIPA5102846 100 μL
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Catalog No. PIPA5102846 Supplier Invitrogen™ Supplier No. PA5102846
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ASC2.

ASC2 associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation. It suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PYDC1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PYDC1
Gene Accession No. Q8WXC3
Gene Alias ASC2; ASCI; cellular POP1; cPOP1; PAAD-only protein 1; POP1; PYC1; PYD (pyrin domain) containing 1; PYDC1; pyrin domain containing 1; pyrin domain-containing protein 1; Pyrin-only protein 1
Gene Symbols PYDC1
Host Species Rabbit
Immunogen A synthesized peptide derived from human PYDC1(Accession Q8WXC3), corresponding to amino acid residues M1-P31.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 260434
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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