Invitrogen™ PYDC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102846

Catalog No. PIPA5102846

Description

Antibody detects endogenous levels of total ASC2.

ASC2 associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation. It suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.

Specifications

• Antigen: PYDC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PYDC1
• Gene Alias: ASC2; ASCI; cellular POP1; cPOP1; PAAD-only protein 1; POP1; PYC1; PYD (pyrin domain) containing 1; PYDC1; pyrin domain containing 1; pyrin domain-containing protein 1; Pyrin-only protein 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 260434
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8WXC3
• Gene Symbols: PYDC1
• Immunogen: A synthesized peptide derived from human PYDC1(Accession Q8WXC3), corresponding to amino acid residues M1-P31.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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