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  5. Tocris Bioscience™ Pyridostatin pentahydrochloride

Tocris Bioscience™ Pyridostatin pentahydrochloride

Catalog No. 476310
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Catalog No. Quantity
47-631-0 10 mg
47-635-0 50 mg
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Catalog No. 47-631-0 Supplier Tocris Bioscience™ Supplier No. 4763/10
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Description

Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest

Binds and stabilizes G-quadruplexes, inducing DNA damage and cell cycle arrest (Kd = 490 nM); targets the proto-oncogene Src, reducing Src protein abundance and Src-dependent motility in human breast cancer cells. Also targets telomeric G-quadruplexes, inducing telomerase dysfunction. Activates the DNA-dependent protein kinase catalytic sunbunit (DNA-PKcs).

Specifications

CAS 1781882-65-2
Quantity 10 mg
Molecular Formula 4-(2-Aminoethoxy)N2,N6-bis[(4-(2-aminoethoxy)-2-quinolinyl]-2,6-pyridinecarboxamide pentahydrochloride
Product Type Pyridostatin pentahydrochloride
Purity 95%
Molecular Weight (g/mol) M.W. (Observed): 778.94
Inhibitors Pyridostatin pentahydrochloride

For Research Use Only

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