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Tocris Bioscience™ Pyridostatin pentahydrochloride

Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest

Manufacturer:  Tocris Bioscience™ 4763/50

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Catalog No. 47-635-0

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.

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Description

Description

Binds and stabilizes G-quadruplexes, inducing DNA damage and cell cycle arrest (Kd = 490 nM); targets the proto-oncogene Src, reducing Src protein abundance and Src-dependent motility in human breast cancer cells. Also targets telomeric G-quadruplexes, inducing telomerase dysfunction. Activates the DNA-dependent protein kinase catalytic sunbunit (DNA-PKcs).
Specifications

Specifications

Pyridostatin pentahydrochloride
>98
50mg
Pyridostatin pentahydrochloride
778.94
1781882-65-2
SDS
Documents
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