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Invitrogen™ Pyruvate Carboxylase Polyclonal Antibody

Catalog No. PIPA585705
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100 μL
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Catalog No. Quantity
PIPA585705 100 μL
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Catalog No. PIPA585705 Supplier Invitrogen™ Supplier No. PA585705

Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Rat (100%), Pig (100%), Rhesus Monkey (100%), Bovine (100%). Positive Control: 293T, A431, HeLa, mouse liver. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Pyruvate Carboxylase requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Pyruvate Carboxylase
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 3.08 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene PC
Gene Accession No. P11498, Q05920
Gene Alias EC 6.4.1.1; Pc; Pcb; Pcx; PYC; pyruvate carboxylase; pyruvate carboxylase, mitochondrial; pyruvate decarboxylase; pyruvic carboxylase
Gene Symbols PC, Pcx
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human Pyruvate Carboxylase. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18517, 18563, 5091
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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