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Invitrogen™ Pyruvate Carboxylase Polyclonal Antibody
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Catalog No. PA550101
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100 μL
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PA550101 100 μL
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Catalog No. PA550101 Supplier Invitrogen™ Supplier No. PA550101
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total Pyruvate Carboxylase protein.

Pyruvate Carboxylase requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Pyruvate Carboxylase
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PC
Gene Accession No. P11498, Q05920
Gene Alias EC 6.4.1.1; Pc; Pcb; Pcx; PYC; pyruvate carboxylase; pyruvate carboxylase, mitochondrial; pyruvate decarboxylase; pyruvic carboxylase
Gene Symbols PC, Pcx
Host Species Rabbit
Immunogen Synthesized peptide derived from internal of human PC (aa 357-406).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18517, 18563, 5091
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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