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Invitrogen™ PZP Polyclonal Antibody
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Catalog No. PIPA559554
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100 μL
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PIPA559554 100 μL
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Catalog No. PIPA559554 Supplier Invitrogen™ Supplier No. PA559554
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QFSINTTSIS VNKLFVRVFT VHPNLCFHYS WVAEDHQGAQ HTANRVFSLS GSYIHLEPVA GTLPCGHTET ITAHYT Highest antigen sequence identity to the following orthologs: Mouse - 42%, Rat - 46%.

The protein encoded by this gene is highly expressed in late-pregnancy serum and is similar in structure to alpha-2-macroglobulin. The encoded protein, which acts as a homotetramer, inhibits the activity of all four classes of proteinases. This protein contains cleavage sites for several proteinases. Upon binding of a proteinase, the conformation of this protein changes to trap the proteinase, limiting its activity. This protein appears to be elevated in the sera of presymptomatic Alzheimer's disease patients.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PZP
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PZP
Gene Accession No. P20742
Gene Alias A1m; A1m {ECO:0000312; A2m; AI893533; alpha 1 macroglobulin; alpha-1-M; Alpha-1-macroglobulin; alpha-1-macroglobulin 165 kDa subunit; Alpha-1-macroglobulin 45 kDa subunit; alpha-2-M; alpha-2-macroglobulin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6; CPAMD6; EMBL:AAA40723.1}; MAM; Pregnancy zone protein; pregnancy-zone protein; Pzp; PZP, alpha-2-macroglobulin like
Gene Symbols PZP
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PZP. Recombinant protein control fragment (Product #RP-98419).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5858
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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