Invitrogen™ QARS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528884

Catalog No. PIPA528884

Description

Recommended positive controls: A549, HeLa, HepG2, HCT116. Predicted reactivity: Mouse (95%), Rat (96%), Xenopus laevis (91%), Chicken (91%), Chimpanzee (100%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family.

Specifications

• Antigen: QARS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: QARS1
• Gene Alias: 1110018N24Rik; 1200016L19Rik; C80286; GLNRS; glutamine-tRNA ligase; Glutamine--tRNA ligase; glutamine-tRNA synthetase; glutaminyl-tRNA synthetase; MSCCA; PRO2195; QARS; RGD1562301
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5859
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.64 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P47897
• Gene Symbols: QARS1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human QARS. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG