Invitrogen™ QDPR Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528041

Catalog No. PIPA528041

Description

Recommended positive controls: Jurkat, mouse liver. Predicted reactivity: Mouse (94%), Rat (96%), Pig (94%), Rabbit (95%), Chicken (83%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.

Specifications

• Antigen: QDPR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: QDPR
• Gene Alias: 2610008L04Rik; 6,7-dihydropteridine reductase; D5Ertd371e; Dhpr; dihydropteridine reductase; HDHPR; HPR; PKU2; QDPR; Quinoid dihydropteridine reductase; SDR33C1; Short chain dehydrogenase/reductase family 33C member 1; short chain dehydrogenase/reductase family 33C, member 1; testis secretory sperm-binding protein Li 236P
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 110391, 5860
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.92 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P09417, Q8BVI4
• Gene Symbols: QDPR
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 244 of Human QDPR.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG