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Tocris Bioscience™ QO 58
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Catalog No. 508350
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Catalog No. 508350 Supplier Tocris Bioscience™ Supplier No. 5083/50
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Kv7 channel opener

QO 58 is a Kv7 channel opener (EC50 values are 0.6, 1.0, 5.2 and 7.0 μM for Kv7.4, Kv7.2, Kv7.3/7.5 and Kv7.1, respectively). Increases the pain threshold of neuropathic pain in a sciatic nerve CCI in vivo model.

Specifications

Chemical Name or Material 5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one
CAS 1259536-62-3
Quantity 50 mg
Target Voltage-gated Potassium Channel Activators
Molecular Formula C18H8Cl2F4N4O
Formula Weight 443.18
Purity >98%
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