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Invitrogen™ QPRT Polyclonal Antibody
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Catalog No. PIPA552866
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100 μL
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PIPA552866 100 μL
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Catalog No. PIPA552866 Supplier Invitrogen™ Supplier No. PA552866
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ALVDSWLRED CPGLNYAALV SGAGPSQAAL WAKSPGVLAG QPFFDAIFTQ LNCQVSWFLP EGSKLVPVAR VAEVRGPAHC LLLGERVALN TLARCSGIAS AAAAAVEAAR GAGWTGHVAG TRKTTPGFRL V Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 84%.

QPRT gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen QPRT
Applications Western Blot
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene QPRT
Gene Accession No. Q15274
Gene Alias 2410027J01Rik; AI647766; epididymis secretory sperm binding protein Li 90n; HEL-S-90n; nicotinate-nucleotide pyrophosphorylase; nicotinate-nucleotide pyrophosphorylase (carboxylating); nicotinate-nucleotide pyrophosphorylase [carboxylating]; QAPRTase; QPRT; QPRTase; quinolinate phosphoribosyltransferase; Quinolinate phosphoribosyltransferase [decarboxylating]
Gene Symbols QPRT
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human QPRT. Recombinant protein control fragment (Product #RP-89649).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23475
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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