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Invitrogen™ QRFPR Polyclonal Antibody
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Catalog No. PIPA575407
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100 μL
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PIPA575407 100 μL
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Catalog No. PIPA575407 Supplier Invitrogen™ Supplier No. PA575407
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. GPR103 is a 455 amino acid protein with highest expression in the brain, retina, trigeminal ganglion, hypothalamus and vestibular nucleus. In peripheral tissues, GPR103 is expressed only in the heart, kidney and testis. GPR103 may regulate adrenal function. A hypothalamic neuropeptide of the RFamide family (26RFa) acts as an endogenous ligand for GPR103.
TRUSTED_SUSTAINABILITY

Specifications

Antigen QRFPR
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene QRFPR
Gene Accession No. P83858, P83861, Q96P65
Gene Alias AQ27; G protein-coupled receptor 103; Gpr103; G-protein coupled receptor 103; orexigenic neuropeptide QRFP receptor; peptide P518 receptor; pyroglutamylated RFamide peptide receptor; Pyroglutamylated RF-amide peptide receptor; QRFP receptor; QRFPR; SP9155
Gene Symbols QRFPR
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 178-334 of Human QRFPR.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 229214, 310327, 84109
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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