QSER1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No.	Quantity
50-156-1703	10 μL

Catalog No. 50-156-1703 Supplier Bethyl Laboratories, Inc Supplier No. A302072AT

Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

QSER1 (glutamine and serine-rich protein 1) is a 1,735 amino acid protein that is phosphorylated upon DNA damage, probably by Atm or ATR. A single nucleotide polymorphism (SNP) that is nearly equidistant between the genes QSER1 and PRRG4 on chromosome 11, at just under 20 kb from each, has been suspected of association with Parkinson disease. Existing as two alternatively spliced isoforms, the QSER1 gene is conserved in chimpanzee, canine, bovine, mouse, rat, chicken and zebrafish, and maps to human chromosome 11p13. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Specifications

• Antigen: QSER1
• Applications: Immunohistochemistry, Immunoprecipitation
• Classification: Polyclonal
• Concentration: 1 mg/ml
• Conjugate: Unconjugated
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene: QSER1
• Gene Accession No.: Q2KHR3
• Gene Alias: Glutamine and serine-rich protein 1
• Gene Symbols: QSER1
• Host Species: Rabbit
• Immunogen: Between 1407 and 1457
• Purification Method: Antigen affinity chromatography
• Quantity: 10 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 79832
• Target Species: Human
• Content And Storage: 4° C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG