Sigma Aldrich (R)-2-hydroxy-4-methylpentanoic acid

Catalog No. CDS006369

Supplier: Sigma Aldrich CDS00636950MG

Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

• 1-acetoxy-1,3-butadiene (1-abd) can be generated by potassium or sodium acetate catalyzed reaction between crotonaldehyde and acetic anhydride. the product is a mixture of cis and trans forms, that has been confirmed by its physical properties and IR spectra. it is reported to be formed as a major product during the acetoxylation of 1,3-butadiene (bd) in gas-phase in the presence of pd-koac (palladium-potassium acetate) catalyst. 1-abd participates as 2+ß or 4+ß diene in cycloaddition reactions. enantioselective diels alder reaction of 2-methoxy-5-methyl-1,4-benzoquinone with 1-abd in the presence of molecular sieves (mesh size:4+a) has been reported.1-acetoxy-1,3-butadiene was used as diene in the following reactions:
• Diels-alder reaction with ortho-carbazolequinones to yield benzocarbazolequinone
• Diels-alder reaction with diethyl ketovinylphosphonate, with and without lewis acid assistance
• Diels-alder reaction with methyl acrylate to yield racemic forms of 2-hydroxy-3-cyclohexenecarboxylic acid. it was used for the reaction with dienophiles such as maleimides, a juglone, a butyne-1,4-dione and methyl 2-(4-methylphenyl)-2h-azirine-3-carboxylate and during visible light photocatalysis. it was also used as reactant during intermolecular oxa-pictet-spengler cyclization

Specifications

• CAS: 20312-37-2
• Molecular Formula: C6H12O3
• Linear Formula: C6H12O3
• MDL Number: MFCD00211263
• Quantity: 10 g
• Molecular Weight (g/mol): 132.16