Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 612450

Tocris Bioscience™ (R)-2-Hydroxyglutaric acid disodium salt, Tocris Bioscience™
GREENER_CHOICE

Catalog No. 612450
Change view
Click to view available options
Quantity:
50 mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
61-245-0 50 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Catalog No. 61-245-0 Supplier Tocris Bioscience™ Supplier No. 6124/50
Only null left
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

KDM4A inhibitor; also NF-κB activator

(R)-2-Hydroxyglutaric acid disodium salt is an oncometabolite produced by mutant isocitrate dehydrogenase 1 (IDH1) and IDH2. Inhibits KDM4A in murine embryonic fibroblasts resulting in activation of mTOR. Also activates NF-κB in bone marrow stromal cells and inhibits FTO (mRNA N6-methyladenine demethylase).

Specifications

Chemical Name or Material (R)-2-Hydroxyglutaric acid disodium salt
CAS 103404-90-6
Synonym (R)-2-Hydroxypentanedioic acid disodium salt
Quantity 50 mg
Solubility Soluble to 100mM in water
Molecular Formula C5H6Na2O5
Formula Weight 192.08
Physical Form Solid
Color White
Product Type Bioactive Small Molecule

For Research Use Only.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.