(R)-CPP, Tocris Bioscience™

Description

Potent NMDA antagonist; more active enantiomer of (RS)-CPP

Highly potent NMDA antagonist; more active isomer. Shows some selectivity for GluN2A (formally NR2A) containing receptors (Ki values are 0.041, 0.27, 0.63 and 1.99 μM for inhibition of GluN2A-, GluN2B-, GluN2C- and GluN2D-containing recombinant NMDA receptors respectively).

Racemate also available.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

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Specifications

Chemical Identifiers

• CAS: 126453-07-4
• Molecular Formula: C8H17N2O5P
• Molecular Weight (g/mol): 252.207
• InChI Key: CUVGUPIVTLGRGI-SSDOTTSWSA-N
• Synonym: r-cpp, chembl47277, 2r-4-3-phosphonopropyl piperazine-2-carboxylic acid, 3-r-2-carboxypiperazin-4-yl-propyl-1-phosphonic acid, tocris-0173, tocris-0247, lopac-c-104, 2-piperazinecarboxylicacid, 4-3-phosphonopropyl-, 2r, --cpp, r-4-3-phosphonopropyl piperazine-2-carboxylic acid
• PubChem CID: 6603754
• IUPAC Name: (2R)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid
• SMILES: C1CN(CC(N1)C(=O)O)CCCP(=O)(O)O

• Quantity: 50 mg
• Formula Weight: 252.21
• Percent Purity: >98%
• Chemical Name or Material: (R)-CPP

Safety and Handling

Recommended Storage

Desiccate at Room Temperature