R&D Systems C16, Tocris™

PKR inhibitor

Manufacturer: R&D Systems 5382/10

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Catalog No. 538210

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Research Use Only. Not For Human or Veterinary Use


    Chemical Name or Material C16
    CAS 608512-97-6
    Assay Percent Range >98%
    Molecular Formula C13H8N4OS
    Formula Weight 268.29
    Synonym 6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one
    Recommended Storage Store at -20°C.
    Quantity 10mg
    Solubility Soluble to 50mM in DMSO and to 20mM in ethanol
    Physical Form Solid
    Product Type Bioactive Small Molecules

    • Rescues PKR-dependent translation block in vitro
    • Decreases Aβ42-induced inflammatory cytokine release and apoptosis in neuronal cultures
    • Prevents neuroinflammation and neuronal loss in an acute excitotoxic rat model
    • Brain penetrant

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