R&D Systems C16, Tocris™

PKR inhibitor

Manufacturer: R&D Systems 5382/10

 View more versions of this product

Catalog No. 538210

  Check Availability
Add to Cart


Research Use Only. Not For Human or Veterinary Use


    Chemical Name or Material C16
    CAS 608512-97-6
    Assay Percent Range >98%
    Molecular Formula C13H8N4OS
    Formula Weight 268.29
    Synonym 6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one
    Recommended Storage Store at -20°C.
    Quantity 10mg
    Solubility Soluble to 50mM in DMSO and to 20mM in ethanol
    Physical Form Solid
    Product Type Bioactive Small Molecules

    • Rescues PKR-dependent translation block in vitro
    • Decreases Aβ42-induced inflammatory cytokine release and apoptosis in neuronal cultures
    • Prevents neuroinflammation and neuronal loss in an acute excitotoxic rat model
    • Brain penetrant

  • Description & Specifications

Related Products

Product Content Feedback

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit