Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 542410

Tocris Bioscience™ Deltarasin
GREENER_CHOICE

Catalog No. 542410
Change view
Click to view available options
Quantity:
10 mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
542410 10 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Catalog No. 542410 Supplier Tocris Bioscience™ Supplier No. 5424/10
Only null left
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

High affinity PDEδ-KRAS interaction inhibitor

Deltarasin is a high affinity PDEδ-KRAS interaction inhibitor (Kd = 41 nM); binds to PDEδ. Reduces proliferation and induces cell death of KRAS-dependent Panc-Tu-1 and Capan-1 pancreatic cancer cells. Attenuates tumor growth of Panc-Tu-1 xenografts in mice.

Specifications

Chemical Name or Material Other Ras GTPase Compounds
CAS 1440898-82-7
Synonym 2-[4-[(2S)-2-(2-Phenyl-1H-benzimidazol-1-yl)-2-(4-piperidinyl)ethoxy]phenyl]-1-(phenylmethyl)-1H-benzimidazole trihydrochloride
Quantity 10 mg
Solubility Soluble to 100mM in water and to 100mM in DMSO
Molecular Formula C40H37N5O·3HCl
Formula Weight 713.14
Physical Form Solid
Product Type Bioactive Small Molecule
Purity >99%

Research Use Only. Not For Human or Veterinary Use

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.