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R&D Systems™ Human MDM2/S5a Ubiquitination Kit

Catalog No. K210
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K210 1 kit
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Description

Designed for in vitro MDM2-mediated ubiquitination of user-supplied substrates such as p53, beta-Arrestin and DYRK

The RING-finger ubiquitin E3 ligase MDM2 (Murine Double Minute 2) is an important regulator of the tumor suppressor protein p53. MDM2 ligase activity is at least partially responsible for the ubiquitination and subsequent proteasomal degradation of p53 and other proteins.

Ubiquitinated proteins can be used in downstream applications, or analyzed by Western blot using antibodies specific for the target protein

Specifications

Content And Storage Store the unopened product at -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Product Type ACTFS, Angiocidin, ASF, HDM2, HDMX, Macropain, Mcb1, MDM2 oncogene, E3 ubiquitin protein ligase, PSMD4, pUB-R5, Rpn10 S5a
Quantity 1 Kit
Gene ID (Entrez) 4193
Gene Symbol MDM2
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