R&D Systems™ Recombinant Human PD-1 Fc Chimera Protein

Description

Extensive quality control produces lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Binding Activity

Measured by its binding ability in a functional ELISA. When Recombinant Human PD-1 Fc Chimera is immobilized at 0.1 μg/mL (100 μL/well), Recombinant Human B7-H1/PD-L1 Fc Chimera (Catalog # 156-B7 ) binds with a typical ED50 of 0.15-0.75 μg/mL.

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Specifications

• Accession Number: Q15116.3
• For Use With (Application): Binding Activity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 5133
• Molecular Weight (g/mol): M.W. (Observed): 60 - 70 kDa, under reducing conditions.
• Name: ASP/C3a desArg
• Quantity: 50 μg
• Source: Mouse myeloma cell line, NS0-derived human PD-1 protein Human PD-1 (Leu25-Gln167) (C-terminus) Accession # Q15116.3 IEGRMD Human IgG1 (Pro100-Lys330) (N-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Structural Form: Disulfide-linked homodimer
• Endotoxin Concentration: <0.01 EU / 1 μg of the protein by the LAL method.
• Gene Alias: CD279, CD279 antigen, hPD-1, PD1, PD1hPD-l, PDCD1, programmed cell death 1, programmed cell death protein 1, Protein PD-1, SLEB2
• Common Name: ASP/C3a desArg
• Gene Symbol: PDCD1
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Reconstitution: Reconstitute at 0.5 mg/mL in sterile PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: PD-1