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Tocris Bioscience™ IHR 1
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Catalog No. 555410
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50 mg
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555410 10 mg
555450 50 mg
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Catalog No. 555410 Supplier Tocris Bioscience™ Supplier No. 5554/10
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Description

Potent Smo antagonist

IHR 1 is a potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro.

Fluorescent Analog also available.

Specifications

Chemical Name or Material IHR 1
CAS 548779-60-8
Synonym N,N'-1,4-Phenylenebis[2,5-dichlorobenzamide]
Quantity 10 mg
Solubility Soluble to 20mM in DMSO with gentle warming
Molecular Formula C20H12Cl4N2O2
Formula Weight 454.13
Physical Form Solid
Product Type Bioactive Small Molecule
Purity >99%

Research Use Only. Not For Human or Veterinary Use

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