R&D Systems IHR 1, Tocris™

Potent Smo antagonist

Manufacturer: R&D Systems 5554/10

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Catalog No. 555410

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Research Use Only. Not For Human or Veterinary Use


    Chemical Name or Material IHR 1
    CAS 548779-60-8
    Assay Percent Range >99%
    Molecular Formula C20H12Cl4N2O2
    Formula Weight 454.13
    Synonym N,N'-1,4-Phenylenebis[2,5-dichlorobenzamide]
    Recommended Storage Store at +4°C.
    Quantity 10mg
    Solubility Soluble to 20mM in DMSO with gentle warming
    Physical Form Solid
    Product Type Bioactive Small Molecules

    • Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways
    • Blocks Smo accumulation in primary cilium in vitro

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