R&D Systems™ Mca-PLGL-Dpa-AR-NH2 Fluorogenic MMP Substrate

Description

Applications: Bioactivity, Binding Activity

• Substrate for MMP-1, MMP-2, MMP-7, MMP-8, MMP-9, MMP-12, MMP-13, MMP-14, MMP-15, MMP-16, Cathepsin D, and Cathepsin E
• Contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2, 4-dinitrophenyl group
• It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence
• Also an excellent substrate for active Cathepsins D and E
• Purity 98±1% based on HPLC

Specifications

• Form: Liquid
• For Use With (Application): Bioactivity, Binding Activity
• Quantity: 1 mg
• Format: Supplied as a stock solution in dimethyl sulfoxide (DMSO) at a concentration of 7.99mg/mL or 6.07 mM.
• Molecular Weight (g/mol): Predicted MW: 1093 Da
• Product Type: Source: Synthetic
• Storage Requirements: Samples are stable for up to twelve months from date of receipt at -20° C to -70° C. The substrate can be aliquoted and stored -20° C to -70° C in a manual defrost freezer for six months. Avoid repeated freeze-thaw cycles. Protect from exposure to direct light.