Tocris Bioscience NS 8593 Hydrochloride
Selective KCa2 (SK) channel negative modulator; inhibits SK currents
Manufacturer: Tocris Bioscience 4597/50
DescriptionSelective KCa2 (SK) channel negative modulator; inhibits SK channel currents (Kd values are 0.42, 0.6 and 0.73 μM for SK1, SK2 and SK3 respectively at 0.5 μM Ca2+). Exhibits selectivity for SK channels over KCa1.1 (BK), KCa3.1 (IK), Kv, Nav and Cav channels. Inhibits afterhyperpolarization in hippocampal slices.
|NS 8593 hydrochloride|
|Soluble to 100mM in DMSO and to 20mM in ethanol|
|Bioactive Small Molecules|
Safety and Handling
Recommended Storage : Store at +4°C.
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Research Use Only. Not For Human or Veterinary Use